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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG2 All Species: 10.3
Human Site: S65 Identified Species: 17.44
UniProt: Q9UNQ0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNQ0 NP_004818.2 655 72314 S65 P V E K E I L S N I N G I M K
Chimpanzee Pan troglodytes XP_526633 860 94544 S270 P V E K E I L S N I N G I M K
Rhesus Macaque Macaca mulatta Q5MB13 654 72441 S65 P V E K E I L S N I N G I M K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q7TMS5 657 72959 D65 V E K E I L S D I N G I M K P
Rat Rattus norvegicus Q80W57 657 72942 D65 A E K E I L S D I N G I M K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510302 654 72378 N65 K E I L H D I N G I M K P G L
Chicken Gallus gallus XP_421638 651 72109 H67 T V E K K I L H N V Y G I M K
Frog Xenopus laevis NP_001091141 661 73548 V65 E R I I L N D V N G I M K P G
Zebra Danio Brachydanio rerio NP_001036240 643 71395 I65 I L I G L N G I M K P G L N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10090 687 75654 N93 S G W R Q L V N R T R G L F C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11180 598 66888 T35 S S G A G K T T L M N V L T S
Sea Urchin Strong. purpuratus XP_789781 628 69714 G65 S L L D I L A G R K E K S G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93YS4 751 82913 M65 S S R R L M G M S P G R S S G
Baker's Yeast Sacchar. cerevisiae P25371 1049 117213 N407 G V E E T V L N E I S G I V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.4 96.6 N.A. N.A. 81.8 81.4 N.A. 75.8 62.4 68.2 60.9 N.A. 31.5 N.A. 29.6 45
Protein Similarity: 100 75.9 97.7 N.A. N.A. 89.6 89.1 N.A. 88.2 78.3 82.1 77.8 N.A. 51.6 N.A. 48.4 63.8
P-Site Identity: 100 100 100 N.A. N.A. 0 0 N.A. 6.6 66.6 6.6 6.6 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 100 N.A. N.A. 26.6 26.6 N.A. 20 80 6.6 20 N.A. 46.6 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.7 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 8 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 0 8 8 15 0 0 0 0 0 0 0 % D
% Glu: 8 22 36 22 22 0 0 0 8 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 8 8 8 8 0 15 8 8 8 22 50 0 15 15 % G
% His: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 22 8 22 29 8 8 15 36 8 15 36 0 0 % I
% Lys: 8 0 15 29 8 8 0 0 0 15 0 15 8 15 36 % K
% Leu: 0 15 8 8 22 29 36 0 8 0 0 0 22 0 8 % L
% Met: 0 0 0 0 0 8 0 8 8 8 8 8 15 29 0 % M
% Asn: 0 0 0 0 0 15 0 22 36 15 29 0 0 8 0 % N
% Pro: 22 0 0 0 0 0 0 0 0 8 8 0 8 8 15 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 15 0 0 0 0 15 0 8 8 0 0 0 % R
% Ser: 29 15 0 0 0 0 15 22 8 0 8 0 15 8 8 % S
% Thr: 8 0 0 0 8 0 8 8 0 8 0 0 0 8 0 % T
% Val: 8 36 0 0 0 8 8 8 0 8 0 8 0 8 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _